DRUG aricept prevelikega INTERACTIONS: Drugs with anti-cholinergic properties that can cross into the brain, such as atropine, benztropine Cogentin and trihexyphenidyl Artane counteract the effects of donepezil and should be avoided during therapy with donepezil. There is evidence to suggest that the frequency of these common adverse events may be affected by the rate of titration. The CIBIC plus is scored as seven point categorical rating, ranging from score of 1, indicating improved, to score of 4, indicating change to score of 7, indicating worse. As in any case of overdose, general supportive measures should be utilized. Embrace all the hate, because without it there would be nothing to appreciate, or love. Eisai, the patent holder on Aricept, is quickly preparing to bring new version of Aricept to the market.