If angioedema of the face, extremities, lips, tongue, or glottis and or larynx occurs, treatment with Lotensin should be discontinued and appropriate therapy instituted immediately see WARNINGS. Discontinuation of therapy has been reported in of patients treated with the drug, compared to of patients treated with placebo. The long-term effects of benazepril on growth and development have not been studied. Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially dizziness. The use of ACE inhibitors during the second and third trimesters of pregnancy has rekkefolge benazepril online been associated with fetal and neonatal injury, including hypotension, neonatal skull hypoplasia, anuria, reversible or irreversible renal failure, and death.