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Use caution when engaging in activities requiring alertness such as driving. Adverse Effects The most common adverse reactions encountered with buspirone are dizziness, headache, drowsiness and nausea. Some anxiety medications can cause withdrawal symptoms when you stop taking them suddenly after long-term use. Adverse events attributable to buspirone may be more likely during concomitant administration with either diltiazem or verapamil. Buspirone has an affinity for brain -dopamine receptors, where it acts as an antagonist and agonist, and et buspirone online for the 5-HT 1A receptors, where it acts as an agonist.